iindaba

Ngomhla we-8 ka-Okthobha, iqela lophando elivela kwiSikolo seKhemesti yeYunivesithi yaseZHONGSHAN lipapashe iphepha kwi-ARCHIVES OF TOXICOLOGY, ijenali ephambili ye-toxicology yehlabathi, ebonisa ukuba kwidosi efanayo ye-nicotine, i-e-cigarette sol ayinabungozi kangako ekuphefumleni. inkqubo kunecubaukutshaya.

Kwiminyaka yakutshanje, imiphumo yezempilo ye-e-cigarettes kunye ne-cigarettes ziye zaxoxisana ngokutshisayo kwintsimi yempilo yoluntu.Kulo phando, iqela lophando leYunivesithi yaseZHONGSHAN liqhathanise imiphumo ye-cigarette kunye ne-e-cigarette ekusebenzeni kwemiphunga, izinto ezivuthayo kunye nokubonakaliswa kweprotheyini kwiigundane ezinomxholo ofanayo we-nicotine, owazalisa i-gap yophando lwezesayensi kwiinkalo ezinxulumene nazo.

Abaphandi basebenzise i-RELX ivatalai-e-cigarettes enencasakunye ne-cigarette yendabuko njengeesampuli, i-32 iyonke iigundane zahlulwa ngokungenamkhethe zibe ngamaqela e-4 kwaye zibonakaliswe emoyeni ococekileyo, i-dose ephantsi ye-e-cigarette sol, i-dose ephezulu ye-e-cigarette sol kunye nomsi we-cigarette kwiiveki ze-10, kwaye i-indexes zabo zahlaziywa.

Iziphumo ze-lung histopathology zibonise ukuba i-lung coefficient yeempuku ezivezwe kwicuba yonyuka kakhulu, kwaye i-morphology ye-trachea yatshintsha, icebisa ukuba inkqubo yokuphefumla inokuba nesifo.Ukuthelekisa, akukho tshintsho lubalulekileyo kwi-coefficient ye-lung kunye ne-trachea morphology kwiigundane ezivezwe kwi-e-cigarettes.

Uvavanyo lomsebenzi wamaphaphu lubonise ukuba ukuvezwa kwecuba kubangele ukungahambi kakuhle kwinani lezalathisi zemiphunga kwiimpuku, kodwa isalathiso esinye kuphela sehla kwiqela le-e-cigarette.Ngelo xesha, iziphumo ze-pathological zibonise ukuba zombini i-cigarette kunye ne-e-cigarette inokubangela ukungahambi kakuhle kwemiphunga kwiigundane, kodwa umonakalo obangelwa yi-cigarette wawucacile.

Ekugqibeleni, umphandi wenze uhlalutyo lweproteomic lwezicubu zemiphunga yegundane.Iziphumo zibonise ukuba utshintsho lweeprotheyini ezihlukeneyo ezibangelwa ugwayi zazigxininise ngakumbi iindlela ezinxulumene nokuvuvukala, ngelixa ukubonakaliswa okungaqhelekanga okubangelwa yi-e cigarette kwakuncinci, kwaye umphumo kwindlela yokuvuvukala evuthayo yayincinci.

Abaphandi bathi iziphumo zibonisa ngokucacileyo ukuba ukuvezwa kweedosi ezinkulu ezifakwe kwi-cigarettes kunye ne-e cigarettes kuyingozi kwinkqubo yokuphefumula.Nangona kunjalo, phantsi kwe-nicotine efanayo, i-e-cigarette sol ayinabungozi kangako kwinkqubo yokuphefumla kunomsi wesigarethi wendabuko.

I-vaping ibonwa ngokubanzi luluntu lwezonyango njengenye indlela engenabungozi kuba ayivelisi tela kwaye ayifuni kutshiswa.